Genetics of Intellectual Handicap Intellectual handicap is one of the primary
indicators for referral to a genetics clinic. It is a characteristic of many
genetic conditions and is also often unable to be classified into a clear
diagnosis. This module will look at the common causes of intellectual handicap
including foetal alcohol syndrome and Fragile X. It will also discuss the
advances in mapping genetic causes of intellectual handicap already underway.
Module Units
Introductory genetics
Taking a family history
Fragile X syndrome
Advances in non-specific X-linked mental retardation
Other causes of intellectual handicap
Learning Objectives
At the end of this module participants will:
Appreciate the frequency of intellectual handicap in the general population.
Appreciate the spectrum of intellectual handicap.
Be aware of the impact of intellectual handicap on families.
Understand the genetic basis of Fragile X syndrome.
Understand the impact of teratogens on pregnancy
Be aware of the advances in the understanding of genetic causes of intellectual
handicap.
Be aware of the difficulty in diagnosing causes of intellectual handicap.
Be able to access patient information and support groups.
